Substance: Tamoxifen citrate
Pack: 50 tabs (20 mg/tab)
Detailed
Tamodex (Tamoxifen Citrate)
This drug is used as a first line defense against breast cancer. In the
late 80´s, Dan Duchaine speculated that it could also be used by
bodybuilders to halt the development of another type of tumor in the
mammary gland, Gynocomastia. He introduced this find to the
Steroid-using-community in his "Contest Prep" issue of the UnderGround
Steroid Handbook Update Newsletters (the contest prep-issue was
actually 3 issues in one, for those who had a subscription to the
newsletter).
Nolvadex is commonly referred to in quite a few ways: as a SERM
(Selective Estrogen Receptor Modulator), as an anti-estrogen (that is
actually incorrect, as we will later see), and finally as a
triphenylethylene. I happen to stick with calling Nolvadex a SERM,
because out of my three options, it happens to be correct (as we know
that calling it an anti-estrogen is incorrect), and pronouncable (as we
know that I have no idea how to say "triphenylethylene"). Selective
estrogen receptor modulators (SERMs) act as either estrogen receptor
agonists or antagonists in a tissue-selective manner, lets see what
that means to us&
Nolvadex actually has quite a few applications for the steroid using
athlete. First and foremost, it´s most common use is for the prevention
of gynocomastia. Nolvadex does this by actually competing for the
receptor site in breast tissue, and binding to it. Thus, we can safely
say that the effect of tamoxifen is through estrogen receptor blockade
of breast tissue (1), especially since total body estradiol increases
with use of tamoxifen. Clearly, if you are on a cycle which includes
steroids which convert to estrogen, you may want to consider nolvadex
as a good choice to run along side them.
Nolvadex Cycle
Nolvadex, however, is not the most potent ancillary compound we can use
on a cycle, but it is probably the safest considering it doesn´t
actually reduce estrogen in your body keeping some estrogen floating
around could have many benefits on muscle growth, as well. Estrogen is
also important for a properly functioning immune system, and not only
that, but your lipid profile (both HDL and LDL) should also show marked
improvement with administration of tamoxifen (4). Many bodybuilders
actually use this stuff during their cycle for the health benefits
provided by it. If, however, you are preparing for a bodybuilding
contest, you need to use something which will suck most (if not all) of
the estrogen out of your body. I am speculating that you may be able to
use Nolvadex for the majority of a contest prep cycle, to keep yourself
relatively healthy, and then switch over to Letrozole for the last 8
weeks.
Nolvadex also has some important features for the steroid using
athlete. In hypogonadic and infertile men given nolvadex, increases in
the serum levels of LH, FSH, and most importantly, testosterone were
all observed (2)(3). The best (rough) estimate I can give you from my
research is that 20mgs of Nolvadex will raise your testosterone levels
about 150% (5)...and this would of course greatly aid
post-cycle-recovery. What this means to us is that if you take Nolvadex
after a cycle, when you are trying to raise your levels of
testosterone, LH, and FSH back to normal, it will greatly aid recovery.
In fact, if I were limited to just one compound to aid me in
post-cycle-recovery, Nolvadex would be my choice. If you want a
comparison, it would require 150mgs of Clomid to accomplish that type
of elevation in testosterone, but nolvadex also significantly increased
the LH (Leutenizing Hormone) response to LHRL (5), after 6 weeks.
Some of the more harsh ancillary compounds available today will give
you a more "dry" look that nolvadex can´t, but nolvadex is simply safer
to use in long (over 16 week) cycles.
Nolvadex Side Effects
Unfortunately, Nolvadex isn´t perfect. Anecdotally, it has been linked
to reduced gains in some bodybuilders. This isn´t due, as previously
thought, to its reducing estrogen levels (which it doesn´t), but rather
to it´s ability to possibly reduce IGF (Insulin-like-Growth-Factor)
levels, which are important for muscle growth.
To Buy Nolvadex Online
Personally, I´ve had many successful cycles with nolvadex as well as
without, but I can certainly testify to it´s effectiveness in
preventing gynocomastia. Back in the late 90´s I purchased 30 tabs of
10mg Nolvadex for $30, and recently I have found it for much less on
various internet sites. It´s well worth the money.
References:
1. Klin Padiatr. 1987 Nov-Dec;199(6):389-91.
2. Stimulation of calcitonin secretory capacity by increased serum
levels of testosterone in men treated with tamoxifen. Int J Androl.
1987 Dec;10(6):747-51.
3. Hormonal changes in tamoxifen treated men with idiopathic oligozoospermia Exp Clin Endocrinol. 1988 Dec;92(2):211-6.
4. 2 Bruning PF, Bronfer JMG, Hart AAM, Jong-Bakker M, tamoxifen, serum
lipoproteins and cardiovascular risk, Br. J. Cancer 1988 Oct, 58 (4)
497-9
5. Fertil Steril. 1978 Mar;29(3):320-7.
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